The dynamic finite element method is used to analyzes the influence on dynamic characteristic of the slope by soft soil layer. The parameters which influencing the earthquake response of the slope, including the depth, the thickness, the obliquity of soft soil layer are analyzed. The influence of soft soil layer is obvious, which must be thought over in the analysis of slope stability. The thicker the soft soil layer is, the more obvious the filter and the amplitude effect is. The deeper the soft soil layer is, the more obvious the filter effect is. The filter effect of the obliquity of the soft soil layer to dynamic time history is not obvious.