To create a model for recycling technology, a waste FR4 printed circuit board (PCB) recycling process employing supercritical fluid CO2 (SCFCO2) is studied using central composite design. The influence of temperature and treatment time on the PCB delamination ratio, latitudinal tensile strength of glass fiber sheets, and their synthesized effect are analyzed. The optimal temperature and treatment time for FR4 PCB recycling with SCFCO2 are found by building a quadratic polynomial equation model of output parameters in recycling technology. The accuracy of the derived optimal temperature and treatment time is validated by a series of experiments.