The absorption of uranium by ionexchange resin is studied based on the characters of pregnant solution for a new uranium insitu leaching mine. The resin types, the absorption parameters and the eluting parameters are chosen in the experiments. The results showd that the 201×7 strong alkaline anion exchange resin and TSF2 anion exchange resin had good absorption and eluting effects. The fixed bed anion exchange absorption is a suitable technology and NH4NO3＋HNO3 mixed solution is an appropriate eluting reagent for this technology.