In order to intensify the process of methanol steam reforming, this paper studies the effect of equally and gradiently distributed catalytic bed on methanol conversion and H2 content at reactor outlet. With the application of general finite reaction rate model in CFD software of FLUENT,2D simulation of this process is carried out.The results show that methanol conversion and outlet H2 content can be increased through gradiently distributed catalytic bed with higher catalytic activity at inlets and lower at outlets. Compared with the equally distributed catalytic bed, the cold spot temperature difference in the microreactor reduces by 10 K, experiment results prove that H2 content at outlets increases about 8.5% and CO decreases by about 0.19%.