The ferronickel submerged arc furnace slags are stored up more and more, as a result, seriously influenced the sustainable development of the nickel industry. By grinding, the ferronickel submerged arc furnace slag is mechanically activated, then can be used as supplementary cementitious material, thus a comprehensive utilization way of ferronickel submerged arc furnace slag is developed. Using such processed slag to replace cement from 10% to 40% in mass, with the increase of replacing dosage, the water demand of standard consistency of cement paste is lowered, the fluidity of mortar is raised; the compressive strength of mortar is decreased; the flexural strength is increased followed by a decrease after the dosage is above 10%, the ratio of flexural strength to compressive strength is increased. The experimental results indicate that the ferronickel submerged arc furnace slag can be used as supplementary cementitious material and has an increase of flexural strength and effect of plasticizing and water reducing.