This paper used FLUENT to simulate the Catalytic combustion characteristics of extremely low concentration methane in microchannel of honeycomb combustor which was coated with catalyst Pt/Al2O3.It analyzed the effect of inlet CH4 concentration, temperature of catalyst wall and inlet fuel velocity on CH4 conversion ratio. The results show that CH4 conversion rate is increases with the increase of inlet CH4 concentration and catalyst wall temperature and the decrease of inlet fuel velocity. When inlet fuel velocity is 0.1 m/s, CH4 volume concentration is 1%, catalyst wall temperature is 950 K, the conversion ratio of CH4 can achieve to 97.0%.