The paper studies the permeability rules of coal during methane sorption and long-term triaxial load by self-manufactured triaxial permeation apparatus. The experimental coal samples are excavated from Fuxin Stratum Coal seam of HengDa Coal Industry Co., Ltd in Fuxin city. The experiment results show that: the value of coal permeability considering methane adsorption is lower than that without methane adsorption, reducing by 48.94%~82.18%; slippage effect exists in coal after sorpting methane. Coal permeability has significant reduce by 82.05%~92.65% under 18 MPa total stress after 78 day, coal permeability variations with time can be described by negative exponential function. The value of permeability of coal sample is higher than that without stress release condition, but is lower than that under initial condition, which is loaded again after stress release. The value of coal permeability is higher than reservoir permeability under initial stratum condition by current experiment methods.