This paper takes Sulige Gas Field as a case study and used three methods including laboratory experiments,production performance analysis and reservoir simulation to study the influence of stress sensitivity on production of fractured tight gas wells.The results show that the fracture length and conductivity of hydraulically created fracture are reduced more than 50%,and the stress sensitivity of hydraulically created fracture is stronger than that of matrix.With the increase of gas production,the influence of stress sensitivity becomes stronger,and finally results in 18% reduction of gas production,and hydraulically created fractures play an important role in the influence of stress sensitivity.