The performance requirements of marine gear box are much higher than that of other gear boxes due to its special working conditions. The structure and transmission principle of a high-power marine gearbox are analyzed, and the experimental test is carried out for the analysis and calculation of its vibration characteristics and intensity. Measured by FFT analysis of vibration signals, the main peak is caused by its octave and the engagement frequency of input stage and middle-class transmission. The vibration severity of high-power marine gearbox reached 4.47 mm/s. In addition, the calculated structure noise of the measuring points is at the 1/3 octaves, and the largest structure noise is 131.27 dB which occurred in the frequency of 329 Hz.