The variation tendency of interface heat transfer coefficient of A356/H13 steel with the thermal-mechanical coupling effects is investigated by using an experimental setup designed by the authors. The results show that，the steady-state heat flow method, which is realized by means of a multiple force amplifier consisting of a pulley force amplifier and a hydraulic force amplifier，can enable the study of the heat transfer coefficient of casting/mold interface with thermal-mechanical coupling effects; the bilateral heating experiments are superior to the unilateral ones; the increase of temperature or load causes the increase of interface heat transfer coefficient in the test range; moreover, the interface heat transfer coefficient at high temperature is more sensitive to temperature than at low temperature, the interface heat transfer coefficient of A356/H13 is nearly linear with the interface load.