A strain Z-2 is originally obtained from sodium desulfurization wastewater and underwent domestication step by step to adapt to high salt content solution. Z-2 is capable of bio-oxidating inorganic sulphuric compound. When NaCl concentrations are 10~20 g/L and 30 g/L, the biological oxidation rate of Z-2 are 90% and 70% respectively. The bioactivity and ability for oxidating sulphuric is completely inhibited when salt content reaches 40 g/L. The optimum cultivation condition of Z-2 are initial pH value of 7.5, temperature of 35 ℃ and ammonium sulfate concentration of 2 g/L. Under this condition, the oxidation rate for the actual wastewater equivalent inorganic sulphuric compound (Na2SO3 70 g/L, Na2S2O3 10 g/L and NaCl 20 g/L) is higher than 95%.