During continuous casting process, the composition of molten steel often varies with different heats, which leads to the big fluctuation of billet surface temperature when the traditional parameter water control model is applied to control the process. Additionally, it is difficult to keep the temperature at the straightening point of the billet within a reasonable range. Given above consideration, a new control model for secondary cooling of continuous casting based on compensation temperature of the difference between liquidus and solidus has been presented. Meanwhile, the temperature field of the billet is simulated with both the parameter water control model and the new secondary cooling control model, and the results indicate that the new control model for secondary cooling of continuous casting could perform better when it is used to control the surface temperature at straightening points of billet, thereby ensuring the quality of the billet.