A dynamic model of NGW helical planetary gear transmission for high-power wind turbine gearbox is established by considering these factors as errors of gears and time-varying mesh stiffness by using mass centralized method. Moreover, the random wind velocity is simulated as external seismic excitation making the results more conform to practical condition. And on this basis, this system is optimized for minimum gearbox volume and minimum component torsional acceleration with the restriction of reliability and strength restrain. The result indicates that the optimized parameters make gear transmission lightweight and the dynamic property improved so as to reduing vibration and noised.