Based on a heavy oil reservoir in Bohai oilfield, a numerical simulation model of cyclic steam stimulation is built based on the characteristics of offshore oilfields. The orthogonal experimental design and numerical simulation are used to optimize the steam injection intensity, steam injection rate, bottom hole steam quality, steam temperature, soaking time and liquid producing capacity. The visual analysis and variance analysis are used to analyze the results. The results show the optimized injection and production parameters are steam strength 20 t/m, steam injection rate 250 m 3/d, the bottom steam quality 0.5, steam injection temperature 340 ℃, soaking time 5d, and the production rate 200 m 3/d. The influence factors on the effect of steam soaking decreased gradually in the following order: steam strength, the bottom steam quality, the production rate, steam injection rate, steam injection temperature, and soaking time. The results can provide theoretical guidance for injection and production parameters optimization of steam huff and puff in offshore heavy oil reservoirs.