By coagulation-activated carbon adsorption treatment of simulated water samples containing Fenpropathrin pesticide, effects on coagulation of coagulant species, dosage, pH and other factors, and wood powdered activated carbon dosage, adsorption time, pH and other factors affecting the adsorption effect are studied. The results show that when water samples are under routine coagulation treatment, the treatment effect of ferric chloride is better than other coagulants. The optimum dosage of ferric chloride is 20 mg/L, the optimal pH is 8, and the highest removal efficiency is up to 59.4%. When water samples are under activated carbon adsorption treatment, the optimal pH range is 6~9, the optimum dosage of wood powdered activated carbon is 40 mg/L, and the optimum adsorption time is 70 min. Under optimum adsorption conditions, fenpropathrin removal rate can reach 81.6%. Under the optimum coagulation adsorption conditions, efficiency to remove fenpropathrin by ferric chloride coagulation collaborating wood powder activated carbon adsorption is greater than 90%, which shows better removal of fenpropathrin.