Scandium content of scandium concentrate in Western Sichuan is 189.80 g/t, and the main scandium-containing minerals are chlorite, montmorillonite, talc and amphibole. The contents of iron, calcium, magnesium are high, and the separation of scandium is difficult. Alkali fusion, hydrolysis, and hydrochloric acid leaching process are applied to the separation of scandium from scandium bearing concentrates in Western Sichuan. The results show that under technological conditions as roasting temperature is 650℃, roasting time 15 min, dosage of sodium bicarbonate 100%, dosage of hydrochloric acid 15%, leaching time 75 min, leaching temperature 45℃, and the liquid solid ratio 1.5:1, leaching rate of 99.56% is obtained. The chemical composition, morphology and energy spectrum analysis of leaching residue show that the main components of leaching residue are silicon, aluminum and magnesium, and scandium content is as low as 4.32 g/t. There is no obvious peak of Sc spectrum in SEM analysis of leaching residue, which indicats that most of scandium is dissolved into liquid phase, thus proving theoretically the effectiveness of alkali fusion-hydrolysis-hydrochloric acid leaching process.