Magnetorheological materials possess excellent intelligent magnetic-control characteristics, offering broad prospects for isolators in complex vibration fields. Currently, most magnetorheological isolators are limited to unidirectional vibration isolation function, with limited research on three-directional vibration isolation applications. Addressing this gap, this paper combines theoretical calculation, dynamic simulation, and finite element analysis to design a magnetorheological three-directional vibration isolator. This isolator, developed for airborne complex vibration conditions, integrates traditional rubber and intelligent magnetorheological fluid materials. A three-directional vibration isolation system is constructed for experimental validation. The experimental results show that the attenuation efficiency for vertical and lateral random vibration reaches 93.93% and 96.01% respectively, demonstrating excellent vibration isolation performance. The design method proposed in this paper for magnetorheological vibration isolators holds significance guiding value and can be extended and applied to other vibration isolators tailored to specific requirements.