To clarify the impact of aerodynamic coupling characteristics on the galloping amplitude of crescent-shaped iced single conductor, an analysis model of wind-induced vibration response of the conductor is established based on aerodynamic theory. The fluid-structure coupling method is used to calculate the displacement time history of the conductor, and the influence of aerodynamic coupling characteristics on its galloping amplitude is analyzed. The results show that the frequency ratio and the degree of freedom have little influence on the aerodynamic lift-drag coefficient of the conductor, which shows that the aerodynamic force on the conductor in the flow field does not change with the different degrees of freedom and frequency ratio. In different degrees of freedom systems, the conductor gallops greatly at the angle of attack of 20°. In the vertical single-degree-of-freedom system, the galloping amplitude of the conductor is greatly influenced by the frequency ratio, and the larger the frequency ratio, the smaller the galloping amplitude. In the vertical-horizontal two-degree-of-freedom system, when the vertical frequency is equal to the horizontal frequency, the conductor is coupled to vibrate, and its galloping amplitude in the vertical direction is greater than that in other frequencies. When the conductor gallops in the flow field, its horizontal movement promotes vertical vibration, and its motion trajectory in the flow field is elongated. The research results clarify the influence of aerodynamic coupling characteristics on the galloping of crescent-shaped iced single conductor, which can provide some theoretical reference for the study of galloping and dancing prevention of the conductor in engineering.