Based on a multi-purpose transmission friction test bench, a variable speed dry friction test was conducted on a lip shaped oil seal made of fluoroether rubber material, taking into account different interference amounts and different media aging times. The effects of media aging time and interference amounts on the torque, vibration, and friction wear of the oil seal installation spindle were studied. The test results show that within the range of parameters selected, with the extension of aging time, the spindle torque decreases, and the vibration decreases first and then increases; With the increase of interference, the torque and vibration of the spindle increase. Moreover, the longer the aging time, the lower the interference, and the smaller the wear amount of the oil seal. In addition, with the increase of aging time, the smoother the friction surface of the specimen, and the more obvious the swelling phenomenon.