The definition of teaching quality supervision and the design principle of teaching quality supervision system are proposed. And the teaching quality supervision and evaluation system of Chongqing University are analyzed and discussed. The results indicate that : 1) Consummating the supervision measures in the process management and the teaching quality supervision and evaluation system considering both construction process and results are the basics of enhancing teaching quality; 2) it is the key to establish a teaching quality supervision and evaluation system with a core of teaching superintending and decision-making, which includes information collection, system and quality evaluation analysis, information feedback, and controlling system.