Analyzing the talent training situation and background of adult higher education in Chongqing, the paper pointed out scientific orientation of talents training target for adult higher education in Chongqing University. With teaching focus of the application- oriented and skill- oriented talents training, strengthening practical teaching management, deepen the reform of teaching practice. According to the summary of practice teaching reform for adult higher education in Chongqing University, constructed practice teaching guarantee system of higher education practice for adult in Chongqing University.