With the development of teaching reform for higher education in China, the quality of higher education and talent training are greatly improved. There is still a problem in higher education; the problem is how to innovate talent training mode to adapt to the urgent needs of the socioeconomic development. Based on the actual situation of Zhejiang University of Science and Technology and the success experiences of other high school, the paper explored the new talent training mode of study groups system with the science research project.