With the development of culture economization and economy culturalization, cultural economy has turned into an important form in the present world. Cultural trade is also playing an increasingly important role in the world trade. In the international cultural trade, some countries set discriminatory provisions for cultural trade based on their own interests, which made the “cultural exception” become the criterion for cultural trade friction. Obliviously, those countries overstated the specialty of the cultural trade. Cultural exception principle is confronting the dilemma both theoretically and practically. Following the micro to macro sequence, the predicament of cultural exception under the WTO framework was discussed first, then the loss due to the cultural trade protection was evaluated based on the benefits analysis, and finally the solution of cultural trade friction under WTO framework was discussed.