In order to implement training requirements of civil engineering excellent program and to improve students’ practice and innovation?abilities of steel structure, steel structure design course need to conduct a comprehensive reform. This paper introduces the course reform content about teaching content, teaching method, practice exercise and assessment method and practical measures in detail. Reform experience shows that engineering applied course should strengthen the concept and introduce logical relationship. The 3D simulation model and case teaching method is helpful for students to master the component composition principle and logical relationship. Assessment should emphasize the students’ innovation ability, practical ability and comprehensive analysis ability. The above has the reference value to the similar engineering courses.