The graduation design of high-rise steel structure in civil engineering specialty has been proposed to satisfy the requirements to the special designers of high-rise steel structures and to improve the ability of undergraduates on applying knowledge of high-rise steel structures. According to some problems in the graduation design, some suggestions on proposing, dispatching and updating graduation design projects, teacher-student interactions, adding related practices, performance appraisals, etc. have been proposed to improve the students’ professional qualities and practice ability.