In China, Hubei University of Technology initiated to set up the waterproof materials & engineering discipline attached to civil engineering in 2005. Based on the collaborative innovation system between college and enterprise, the aim of the discipline is to cultivate high-level application-oriented talents to meet the continuous development of waterproof industry. We summed up the discipline construction experience of waterproof materials & engineering from aspects of running ideas, talent training mode and implementation measures, which can be a reference for engineering talent training mode reform in other universities.