According to the “multi-media, engineering case studies and numerical simulations” teaching model and knowledge modules, actual engineering cases were selected as teaching subjects, and numerical simulation experiments based on finite element software and multimedia technology were applied in teaching of earthquake-resistant of structure. In this sense, students were attracted into a real seismic engineering situation and the visualization of course contents was realized. Meanwhile, teachers and students were interacted. By using the teaching model, students’ ability to understand basic conceptions of earthquake-resistant of structure and their practical application ability were improved.