Case teaching adopted in steel structure courses will help improve the teaching efficiency and quality, but problems such as case scattered and related courses taught respectively exist in the implementation process, which is not conducive to the establishment of students'overall design thinking and cultivation of comprehensive ability. Based on case, this article conducts the research and practice on integrated teaching of steel structure curriculum. Taking three case that angle steel roof truss, single-story portal frame warehouse, multi-story steel frame laboratory building as the main line to carry out teaching, to realize the integrated teaching with three levels of basic design theory, the element design, and configuration integrated design, then finally realize the students application ability.