It is a common problem in the experimental teaching that the introductions of large equipment and special equipment are limited. In order to guarantee the effect of experimental teaching, the concept of the remote resource sharing of large-scale equipment was brought forward based on the method of combination of virtual and reality, which was proposed during the construction of the national virtual simulation experimental center of Southeast University. By using the self-developed hardware and software, solutions were obtained for the remote resource sharing laboratory development. Through the remote desktop sharing and multi-angle video sharing, remote control, operation and experimental teaching of large equipment can be accomplished, which enabled the students to operate and analyze test data in personal. The results show that, the problem of low utilization efficiency of large equipment in the laboratory construction can be overcame, comprehensive experimental courses can be established by remote resource sharing of equipment, which solved the problem of equipment lack and improves the practical ability of students.