At the rapid improve time of China's society-economy and economical structure, the progress of excellent engineers training program improves the country's self-dependent innovation ability and core competitiveness enormously. Civil engineering is a practical discipline, enhancing the practical teaching reform plays a crucial role in cultivating excellent engineers who can hold high comprehensive vocation ability, advanced innovative awareness and practical skills. Random vibration of engineering structures is an application course which studies the stability, responses and reliability of structural systems using probability and statistics methods. Now, handling or at least acquainting the random vibration methods in engineering structure's design is a basic requirement for a well-educated civil engineer. A well-educated civil engineer is expected to understand the basic concepts and practical methods of random vibration. In this paper, the course characteristics are focused squarely such as confusing conceptions, complicated formulas and abstract mathematical descriptions. By summing and discussing the teaching activities of random vibration of engineering structures course in the College of Civil Engineering, Tongji University, this paper systematic illustrates and overall reviews the guidance and appropriate practice methods in the teaching activities of random vibration of engineering structures. The illustration and review are dissected from the following four aspects:basing on the theoretical education, introducing the course developing trend, focusing on students' practical skills and developing the flexible evaluation criterion. The methods in this paper are believed efficient and reliable to guide students mastering theoretical concepts, to motivate students, and to develop the students' practical abilities. It has shown the satisfied teaching effect in the practice teaching.