The rapid development of we-media has changed the way people obtain and disseminate information. Its characteristics of popularization of the disseminator, diversification of content, and immediacy of speed have also brought opportunities and challenges to college students' Party construction. In order to improve the students' Party construction, colleges should make use of its advantages and disadvantages from the aspects of education of Party members, construction of we-media platforms, construction of Party construction teams, etc., in we-media environment. At the same time, this work can give play to the ideological leading role of the Party organizations, improve the work efficiency of Party organizations, and create new types of specialized Party construction team.