With the rapid development of science and information technology the traditional mechanics classroom and teaching methods have been greatly impacted. The teaching method of mechanics should follow the development of science and technology and the reform of mechanics teaching must be carried out. Taking engineering mechanics course as an example, this paper points out the position and importance of this course in professional talent training program, summarizes the problems existing in the teaching practice of engineering mechanics course under the traditional teaching mode, introduces the construction process of interactive mobile learning system based on learning mobile application, proposes a hybrid teaching mode of "classroom teaching + application of interactive mobile learning system" and performs the student satisfaction survey and teaching effect validation after the practice, points out the advantages and disadvantages of the hybrid method teaching to provide reference for the teaching reform of mechanics course in universities.