MOOC, the massive open online course, is an important form of a combination of information technology and education. It provides support and guarantee for blended teaching and plays a crucial role in boosting the education revolution and intensive development for college and university courses. Based on the national excellent resource sharing course design of concrete structure at Wuhan University (abbreviated as concrete structure), the MOOC course construction is carried out. The curriculum structure is transformed and optimized through content reconstruction, teaching design and online applicability, and the curriculum characteristics are formed. Based on the OBE concept, according to the degree of difficulty of knowledge points, different levels and forms of blended teaching mode are constructed, and corresponding evaluation methods are established. Practice shows that it can stimulate the enthusiasm and initiative of students and improve the quality of teaching.