Big data has become a powerful driving force for the innovation and development of college moral education, actively integrating into big data era is not only the demand of information age, but also the inevitable requirement to implement the fundamental task of moral education in the new situation. The broad application prospect of big data in college moral education needs to be considered from the premise of value, that is, to construct the basic principles of the application of big data in college moral education from the perspective of methodology. To be specific, it includes the unity of optimism and prudence, the coordination of technology and humanity, the combination of group and individual, and the harmony of rights and responsibilities. Only by clarifying the cognitive bias, can we provide ideological guidance for relevant data application subjects, and effectively avoid the practical errors in the application of big data in college moral education.