According to the high order, innovative and challenging standard, the construction objectives and principles of the honor course of fluid mechanics are determined in terms of teaching syllabus reconstruciton, teaching method innovation, teaching team construction, student selection and assessment requirements and so on. The characteristics of this honor course includes: problem-driven as the starting point, basic concept as the fulcrum, learning output as the guidance and virtual simulation practice teaching as the expansion. Four forms of continuous equations and their relationship with different flow models, computational fluid dynamics technology in virtual simulation platform and progress of modern fluid measurement technology are taked as examples to illustrate the high-order requirement in course content, innovative requirement in virtual study platform and challenging requirement in students’ learning output. Such attempt can provide reference for the construction of honor courses of fluid mechanics and other mechanics in engineering displine.