As an important part of teaching work in colleges and universities, experimental teaching plays an irreplaceable role in polishing students’ ability to analyze and solve problems, especially for local application-oriented universities. It is an important way to cultivate college students’ practical operation ability, innovation ability, practical ability and entrepreneurial spirit. In order to explore the construction mode of open experimental platform in local application-oriented colleges, this paper takes the road and bridge laboratory of Civil Engineering and Architecture College of Hubei University of Arts and Science as an example, points out the problems existing in the current undergraduate experimental teaching from the aspects of curriculum and teaching management, and puts forward the reform measures of the open experimental platform, including developing an open intelligent comprehensive experimental management platform that integrates experimental project selection, online course cloud sharing and experimental instrument reservation, constructing the two-way selection terminal elimination system, improving the course evaluation mechanism that focuses on students’ practical ability, and establishing a special safety management system covering all teachers and students. The open experimental platform stimulates students’ practical ability and innovation potential, improves the utilization rate of experimental equipment and teaching resources, and lays a solid foundation for cultivating people with virtue and better cultivating application-oriented professional and technical talents.