With the transformation and upgrading of the civil engineering industry, the integration and penetration of specialties are more significant. Taking the major of civil engineering at Yangtze University as an example, a multi-professional collaborative education practice is carried out. Firstly, the internal logic of civil engineering talent training is analyzed from the aspects of curriculum ideological and political education, professional ideological and political education, and multi-professional collaborative ideological and political education. In combination with professional courses, professional characteristics, and cognitive rules of students, a multi-professional collaborative education path is proposed. Secondly, the value index of multi-disciplinary collaborative education in civil engineering is constructed by analyzing the industry’s demand for talents， and a multi-professional ideological and political value chain led by ideological and political education is formed. Finally, taking curriculum ideological and political education as a starting point, professional ideological and political education as a focus, and multi-professional collaborative ideological and political education as the goal, the talent training mode of one body and two wings of civil engineering is constructed. The research results have been popularized and applied in the civil engineering and architecture major of Yangtze University, and have achieved good educational effects, which can be used for reference by peers.