In professional degree postgraduate education, professional practice, as a unique and important cultivation link, is not only a key process distinguishing it from academic postgraduate cultivation, but also an important institutional design for testing the quality of professional degree postgraduate education and the effectiveness of reform. With the help of CiteSpace data analysis and visualization tool, 1110 papers in China National Knowledge Infrastructure(CNKI) are used as research samples, and bibliometric method is adopted to systematically describe and analyze the number of publications, core authors and partnership network, frontiers, and hot topics in the field of professional practice of professional degree graduate education in the past two decades (2000-2024). The analysis results show that there is a general upward trend in the number of publications on the professional practice of professional degree students. There is little cooperation between core authors and research institutions, and the research hot topics are greatly influenced by national policies and social demands, the core themes are practice bases, cultivation modes, dual tutorship, teaching reform and practice innovation, etc. The research hot topics are gradually shifted to the integration between industry and education and classified training modes. In the future, the reform of professional practice from aspects such as the innovation of differentiated talent cultivation, the integration between industry and education, and the process management and effect evaluation guided by value-added and comprehensive orientations should be further explored to improve the quality of talent cultivation of professional degree graduate students.