In the current rapidly developing economic and technological environment, the civil and architectural engineering industry is facing new challenges and opportunities. To meet the demands of the new era, cultivating talents with interdisciplinary knowledge and comprehensive abilities has become an important direction for education reform in this industry. Based on an analysis of the demand for talents in the new era of civil engineering and architecture, this article explores how to cultivate strong cross-disciplinary talents through the construction of computer-aided engineering (CAE) courses and summarizes the basic experience of CAE course for civil and architectural engineering construction and reform.