With the further development of educational informatization, knowledge graph, as a new educational technology, is widely used in the construction of curriculum resources. Taking the course of real estate development and business management as an example, this study explores the construction method and path of knowledge graph educational resources on virtual teaching and research classroom curriculum. Firstly, a set of systematic curriculum knowledge graph construction framework is proposed, including key steps such as the construction of data layer and pattern layer, ontology construction, information extraction, knowledge processing and fusion. Secondly, it constructs the three-layer structure of the knowledge–problem–ability graph of this course. Teaching effect shows that the curriculum teaching resources based on knowledge graph can effectively improve the teaching quality, promote students’ active learning, and provide a new perspective and practice path for curriculum reform.