Civil engineering is a practical subject, therefore, the cultivation of civil engineering talents need combine with practice. There is a significant meaning for improving cultivation quality by production, teaching and research model. Combining with more than ten years teaching experiences, the civil engineering talents training model with integration of production-university-research has been created. In summary, colleges need cultivate more inter-disciplinary talents who can meet the needs of society, and corporations have to submit professional and technical requirements according to their needs. Only through the way to building a system of production-university-research cooperative education that integrates "collaborative education", "collaborative teaching", and "collaborative innovation" by colleges and corporations together, can it promotes the cultivation of civil engineering talents in the integration of production-teaching-research effectively.