Under the background of the national strategy of "building a powerful country with transportation", the construction of transportation infrastructure urgently needs to be guided by "two new and one heavy" to meet the requirements of intelligent transportation in the new era. As the main body of professional talents training, colleges and universities should encourage the two disciplines of transportation engineering to cross with other disciplines according to the national strategy and industry demand, push the transportation engineering specialty closer to the direction of intelligence and informatization, and systematically reform the postgraduate training mode. Based on the problems existing in the current training system, this paper summarizes the core competencies that postgraduates in transportation infrastructure should have. On this basis, supported by curriculum system, training mode and interdisciplinary, and guaranteed by management methods, tutor team and practice platform, this paper puts forward the idea of the reform of postgraduate training mode in the cross direction of intelligent transportation infrastructure. At the same time, it points out the possible problems in the exploration of the training mode, and provides a perfect and feasible scheme for the postgraduate training in the cross direction of intelligent transportation infrastructure.