Labor education and innovation and entrepreneurship education have isomorphic symbiosis in connotation, goals, contents, methods and other aspects. The new situation of coordinated development of labor education and innovation and entrepreneurship education has put forward new requirements for the training of talents in road, bridge and river crossing engineering majors in higher education institutions. Subgrade and pavement engineering is the core course of road, bridge and river crossing engineering majors, which bears the important task of curriculum education. It always focuses on students, establishes the trinity curriculum goal, takes moral cultivation as the fundamental goal, and builds a education model that closely combines labor education, innovation and entrepreneurship education and professional education. Through the creation of hybrid online learning space, labor education and ideological and political education, group competition teaching, competition research to promote learning, diversified evaluation and other ways to practice knowledge, enhance students" labor innovation awareness and ability, improve the quality of school talent training. This course has a positive reference significance for promoting the reform of the curriculum of "integration of labor and innovation" in Chinese universities.