In the face of a new round of scientific and technological revolution and industrial transformation, high-level innovative talents have become the core strategic resources for building a scientific and technological power. As the key combination of the first productivity of science and technology, the first resource of talents and the first driving force of innovation, [ 1 ] higher education shoulders the historical mission of cultivating national strategic talents. In order to realize the effective improvement of college students ' innovative practical ability, we must deeply understand the connotation and essence of the concept of strengthening the country through science and technology, accurately grasp the deep-seated requirements of the strategy of strengthening the country through science and technology for the cultivation of higher education talents, and fully consider the stage law of the formation of college students ' innovative practical ability and the three influencing factors of ' individual-college-society '. This study systematically discusses the theoretical logic and practical methods of improving college students ' innovative and practical ability under the guidance of the concept of scientific and technological power. Based on the practical exploration of the Internationalization Demonstration College of Materials Science and Engineering of Wuhan University of Technology, this paper puts forward the practical path of ' based on interdisciplinary project-based learning, expanding the vision with international integration, anchoring the direction with the integration of production and education, and stimulating the source with multiple evaluations ', in order to provide theoretical reference for deepening the reform of higher engineering education and improving the quality of independent training of talents.