Currently, there are a lot of problems in risk assessment for a clean and honest administration in universities and colleges, including uncertain standards, indeterminate point in time, nonstandard procedures, and unclear results. Concepts and methods of project management and risk management were introduced to construct a life cycle risk assessment system for a clean and honest administration in universities and colleges. It will be helpful for the perfection of risk prevention mechanism to achieve a goal of timely identifying, analyzing and avoiding the risk.