Concrete structure design principle is a very important major required course of civil engineering. Its teaching quality directly affects the students' study of follow-up courses. Based on the characteristics of the course and the actual teaching situation, the teaching method of the course is reformed, mainly including making full use of multimedia technology, analyzing of formula connotation deeply, strengthening practice teaching, paying attention to the cultivation of innovative ability, perfecting network platform construction and reforming examination methods, etc. The implementation results show that the measures of teaching reform suggested in this paper are reasonable and effective.