Abstract:During the social transition, selfattack is seen more often than not among college students. Selfattack is a form of emotional release for selfextrication at the sacrifice of the individual’s own living organism. Selfattack may results in physical injury or even loss of life, and is then referred to as extreme selfattack. Exploring the generation of college students’ extreme selfattack psychology and finding the effective preventive measures are of great practical significance for students’ healthy development and social harmony and stability, which is also a requirement from the humanbased educational concept. This article analyzes some statistical data on the college students extreme selfattack in China from 2004-2008, explores the direct and social causes of the behaviors and points out that the generation of college students’ extreme selfattack psychology is characterized by staged development, externalization, negation and controllability. The countermeasures for preventing college students’ extreme selfattack are proposed from the perspective not only of “cure the symptoms” but also of “cure the disease”.