All main drug consuming countries in the world consider drugs as a special commodity to supervise, so governing the drug circulating channel is becoming an important job in government's management. Since multi-market subject had been drawn into the drug circulation in China in 1984, drug circulation started to compete disorderly, hence many issues, such as: virtual height in drug price, polypharmacy in hospital, appeared. Therefore, the State and each local government try to explore drug circulation control mode. However, before the orientation which basic medical treatment in new medical reform returns to public welfare was put forward to, measures for treatment almost were immersed in interest gaming among multi subjects in channel and babbling policy argument. By professional survey and evaluation to drug circulation governing before and after carrying out basic drug system in China, the paper found the difficulties and defects in drug circulation channel control. By taking the successful experiences as references in drug circulation control gained by those main drug consuming countries in the world, it suggests that the government should focus on rational medical behavior supervising and scientific drug pricing, active leading drug circulation to large-scale operation