To pay attention to the mental health and social support of the elderly retired in university is an important content of university retired work under the new situation. Based on a survey of Chongqing’s universities, combined with the situation of domestic norm and Guangdong’s universities, this research explores the status of mental health and social support in all aspects of the relationship and characteristics. The result shows that the scores of mental health and social support of retired elderly in Chongqing’s universities are significantly higher than the whole norms of China. There is a positive correlation between mental health and social support. Improving the physical health and cognitive level is conducive to mental health. Finally, this research provides countermeasures and suggestions to promote mental health status of retired elderly in university through improving the elderly education and guidance, carrying out mental health consultation and strengthening the service.