Faced with the increasingly complex situation of global economy, China’s pattern of economic globalization needs a drastic change in direction from focusing on away market to home market. The new pattern of economic globalization performs greater connectivity of domestic and foreign markets based on expanding domestic demand, and drives domestic enterprises to participate in the dual cycle of domestic and foreign markets with the development and growth of the domestic market. The key to China’s economic globalization in home market is to use domestic demand as a strategic basis, increase the input of advanced production factors, and transform the global value chain into a global innovation chain that can promote industrial upgrading. This need coordinated work which includes the theory of dynamic comparative advantage as guidance, the domestic value chain as support, the modern industrial clusters as carriers, the Internet Plus digital economy as opportunities, and the Belt and Road Initiative as links. Moreover, the most important basis and precondition is to make the domestic market unified, open, competitive and orderly as soon as possible. Its specific policy directions are resolutely protecting the vitality of market entities, building economic platforms to expand domestic demand and paying more attention to opening up internally.